THE topic is going to be on the plague disease • Written as a scientific review paper.
• Must include at least 10 references (scientific references are texts or peer reviewed journals, not websites) • Must be at least 12 pages, double spaced, Arial or Times Roman 12 point font, 1 inch margins – Not counting cover page or references cited. – Images, tables, graphs should all be on their own page, with figure text below (these do not count towards the 12 pages).
Reports • Report must include 4 sections (10 points each): – History of the disease (discovery, identification, important cases, important breakthroughs, etc.)
– Biology/symptoms of the disease
– Epidemiology/transmission of the disease, including current research
– Mathematical modeling of the disease • Each section must be at least 2 pages.
– Epidemiology section must be at least 4 pages
• Note
– not just about the biology of the pathogen! • Questions to answer in your report:
– Where did the disease originate?
– When it was first observed? Who discovered it? How did they identify it? What misconceptions did they have initially about the disease?
– Major outbreaks, epidemics, or important cases (ones that changed our understanding of the disease) Report: Biology/Symptoms
• Biology/Symptoms of the disease
– What is it? (virus, parasite, bacteria, etc)
– What effect does it have?
– What are the symptoms?
– Is it treatable? How is it treated?
– Is it terminal? Chronic? Report: Epidemiology
• Questions to ask:
– How does it spread?
– How do symptoms influence transmission?
– What is a case definition? Who developed this? How has it changed?
– Who is at risk/what are the risk factors?
– What happens during an outbreak (response)?
– How do we engage in surveillance?
– How bad is the infectivity? Pathogenicity? Virulence?
– What are morbidity and mortality rates? Survival rates?
– What are the current incidence and prevalence numbers?
– What happens after you get the disease?
Report: Epidemiology
• Can it be controlled? Eradicated? If so, how?
• What past control/eradication efforts have there been? Why did they not work (or if they did, why did they work?)
• What kind of epidemiological research is being done on the disease?
– Give specific examples, including research results
– Current research is NOT vaccines and treatment Report: Modeling
• What kind of mathematical models are used to make predictions about this disease?
• What are some of the variables that have been calculated (R0, transmission rate, recovery rate, etc)?
• How accurate are the predictions?
• How has a model been used in control or eradication?
• Give an example of a model, and the predictions that it has made.
– The model should be specific to the disease, not just repeating what we learn in class