Identify and experimentally validate a gene and the mutations in that gene that seem to cause a human monogenic disease
Identify and experimentally validate a gene and the mutations in that gene that seem to cause a human monogenic disease.
Identify and experimentally validate a gene and the mutations in that gene that seem to cause a human monogenic disease.
Paper details:
– USE Vancouver style references and high impact journals. – please don’t skip the questions. solve them all and follow all instructions carefully – see previous year assignment and pay attention to the comments so you don’t do the same mistakes – answer each question alone and put subheadings for each answer. don’t combine the answers. divide into sections. – no plagiarism
Your screening methodology must come from the the United States Preventive Services Task Force guidelines – use the attached link. https://www.uspreventiveservicestaskforce.org/Page/Name/recommendations Explain the guideline, the correct application of the screening, and the epidemiology behind the guidance. Content required should include epidemiologic data such as statistical information as available ex. morbidity, mortality, incidence and prevalence of condition. Identify risk factors, risk assessment, testing interval, description of the patient population, screening test recommendations and other factors relative to the guideline.
Description
parts of my research outline titled sections 5 and6 (highlighted for convenience) expanded to be a minimum 5 pages a section. Incorporating a minimum of two of the supplied references in each section, no direct quotation, paraphrasing only. No references other than those supplied. Each paragraph must have a citation. All assertations must be substatiated and must be cited.
This is a social work class that explains the the 6-stage treatment process Purpose/Overview: The purpose of this assignment is to practice conceptualizing a trauma-informed treatment plan that outlines an appropriate sequence of treatment. Format: You will use the findings from your case conceptualization to develop a treatment plan using the materials provided for you in the course shell. Specifically, your treatment plan will provide specific details about and suggestions for working with the client during the following stages of treatment and address all of the questions under each section: Evaluation What are the primary goals of this stage of treatment? At what stage of trauma treatment is the client currently? What are the client’s long and short-term goals, and how are your treatment recommendations designed to help the client reach them? How might you build rapport/trust with the client (and their family, if applicable)? Safety/Stabilization What are the primary goals of this stage of treatment? What specific rules/expectations/agreements might you need to establish with the client to help to ensure safety during and/or between sessions? How come? What are your recommendations in terms of case management (e.g. safe housing, medical care, transportation, educational placement, etc.)? How come? What do you suggest to help the client manage unnecessary stressors/triggers? What type of training do you suggest for family members to help the client feel safe and secure at home/in the relationship? How come? Skill/Strengths Building What are the primary goals of this stage of treatment? What types of skills and strategies do you suggest to help the client manage their anxiety symptoms? How come? What types of skills and strategies do you suggest to help the client improve their coping behaviors and outcomes? How come? What progressive challenges might you suggest to help increase the client’s sense of accomplishment, strength, and/or affect tolerance? How come? Trauma Resolution What are the primary goals of this stage of treatment? How will you know when the client is ready for this stage? What do you suggest in terms of the order for targeting memories? How come? What do you suggest in terms of an exposure strategy? How come? What additional skills/strategies do you suggest using with clients during this phase of treatment to help ensure safety, containment, relaxation, and/or recomposure during and after exposure? How come? How might progress be monitored/evaluated? Consolidation of Gains What are the primary goals of this stage of treatment? What do you suggest to help the client overcome remaining symptoms after trauma resolution treatment? How come? How might you and the client identify and resolve remaining problems or challenges? Relapse Prevention and Harm Reduction What are the primary goals of this stage of treatment? What suggestions do you have for this stage of treatment? How come? General Expectations: Remember to provide rationales for your suggestions: the “how come” is as important as your recommendations.
Value Proposition in Patient Care Academic Level : Professional Paper details Paradise Hospital, Inc. is a for-profit hospital. As the facility’s new hospital administrator, you have been tasked with improving the service value of the hospital. The administration has not done this process since the hospital began operating in the year 1995.
The investors are not familiar with the value proposition strategies of hospitals in the current day America. Note: You may create and / or make all necessary assumptions needed for the completion of this assignment. Write a four to six (4-6) page paper in which you: Articulate the meaning of value-added service as it pertains to patient care services, and argue the major reasons why it matters to add value to patient services. Justify your response. Outline a system for identifying the functional areas in which changes might be necessary in order to improve the hospital’s service value.
Recommend the key methods that you would use to acquire the information necessary to identify the specified functional areas. Specify four (4) specific areas where you believe the administration can add value in Paradise Hospital, and argue the most significant reasons why such value proposition would improve the value of services to the patients. Use four (4) recent (within the last five [5] years) quality academic resources in this assignment.
The proposal must be from Medical Radiation Physics viewpoint. The proposal content must follow: -Proposed thesis title -Table of contents -Background -Research question -Purpose & aims -Significance -Literature review -Research design (experimental and methodological approaches) -Timeline or plan (4 years) -Expected outcomes -References The research proposal must concentrate on the performance and accuracy of Radiation Dose Calculation Algorithms in terms of a successful lung cancer radiotherapy. As much as sources as possible to be used to ensure that they cover all aspect of the topic.
Papers are to be well written in a scholarly manner with proper APA formatting and citation of sources. o Please remember you will need a minimum of 3 scholarly nursing articles for your paper that are selected from the pre-approved list. (Any article that the student selects that is not on the list must 1st be approved by the course professor). o Other appropriate materials that can be used in addition to the scholarly article- relevant RNAO BPGs and relevant scholarly authoritative sources (e.g., WHO, Health Canada), your Perry et al text- in addition to the scholarly journal article. o You may use Health Canada or Potter & Perry text for your selection of the relevant determinant of health
Instructions below: research paper (20%): You are required to write a research paper on a topic approved in advance.
The topic should indicate a positive correlation between a psychological diagnosis and specific criminal behavior. Papers are expected to adhere to standards set forth in the American PsychologicalAssociation’s Publication Manual (6th Edition). Papers will be 8-10pages in length (excluding title page & references) and include at least 10references from professional journals. Papers with less than 8full pages of the body (in APA format) are incomplete and will receive a 0. Late assignments will not be accepted.
The final paper must be submitted as a hard copy at the start of class on the due date. Students are also required to submit an electronic version through blackboard by the beginning of class on the due date. Final papers are due on October 29, 2019. Students are encouraged to visit the Writing Center (NB 07.68) for assistance with thesis development, grammar, and punctuation. For assistance with conducting research, students should visit the Library. Grading criteria for the paper is as follows: Adherence to APA standards
A Case Study in Regulation Background On January 17, 2006, FDA issued a direct final rule/proposed rule to exempt investigational drugs and biologics for phase 1 human clinical trials from the cGMP regulation.
As you know, it is a requirement that all clinical and commercial drugs and biologics, such as vaccines, be made per cGMP regulation. At the same time, FDA issued a draft guidance providing recommendations on manufacturing Phase 1 material (to replace the formal, legal cGMP regulation).
FDA was proposing to regulate Phase 1 material by means other than cGMP regulation, by relying on the broad applicability of the Food, Drug, and Cosmetic Act (which states that drugs not made per cGMPs are adulterated, but does not provide specifics) and by the information submitted in Investigational New Drug (IND) Applications by sponsors. FDA stated that they were taking the action “to streamline and promote the drug development process.”
Preparation Read the following documents to prepare yourself for an essay response on this proposed rule: FDA Guidance for Industry: INDs – Approaches to Complying to cGMP during Phase I (read sections I through V)Preview the document History of GMPs
– Power of Storytelling article by Barbara ImmelPreview the document Barbara Immel comments on Direct Final/Proposed RulePreview the document Optional: Chipping Away the GMPs (Powerpoint slides as a pdf) by Barbara ImmelPreview the document Essay The events and comments surrounding the FDA proposal to eliminate formal cGMP adherence for Phase I studies led the Agency to withdraw the rule on May 2, 2006 due to the significant adverse comments they received by individuals and groups, such as the Immel Group. This result is important because it is a timely reminder of the complexity involved in changing regulation and also the impact that the public can have on shaping how the FDA regulates this industry. Write a three-page essay (12-pt font, double-spaced) based on your experience in this course and the preparatory readings above that addresses the following prompt:
Description Evaluate the Health History and Medical Information for Mr. M., presented below. Based on this information, formulate a conclusion based on your evaluation, and complete the Critical Thinking Essay assignment, as instructed below. Health History and Medical Information Health History Mr. M., a 70-year-old male, has been living at the assisted living facility where you work. He has no know allergies. He is a nonsmoker and does not use alcohol. Limited physical activity related to difficulty ambulating and unsteady gait. Medical history includes hypertension controlled with ACE inhibitors, hypercholesterolemia, status post appendectomy, and tibial fracture status postsurgical repair with no obvious signs of complications. Current medications include Lisinopril 20mg daily, Lipitor 40mg daily, Ambien 10mg PRN, Xanax 0.5 mg PRN, and ibuprofen 400mg PRN. Case Scenario Over the past 2 months, Mr. M. seems to be deteriorating quickly. He is having trouble recalling the names of his family members, remembering his room number, and even repeating what he has just read. He is becoming agitated and aggressive quickly. He appears to be afraid and fearful when he gets aggressive. He has been found wandering at night and will frequently become lost, needing help to get back to his room. Mr. M has become dependent with many ADLs, whereas a few months ago he was fully able to dress, bathe, and feed himself. The assisted living facility is concerned with his rapid decline and has decided to order testing. Objective Data Temperature: 37.1 degrees C BP 123/78 HR 93 RR 22 Pox 99% Denies pain Height: 69.5 inches; Weight 87 kg Laboratory Results WBC: 19.2 (1,000/uL) Lymphocytes 6700 (cells/uL) CT Head shows no changes since previous scan Urinalysis positive for moderate amount of leukocytes and cloudy Protein: 7.1 g/dL; AST: 32 U/L; ALT 29 U/L Critical Thinking Essay In 750-1,000 words, critically evaluate Mr. M.’s situation. Include the following: 1)Describe the clinical manifestations present in Mr. M. 2)Based on the information presented in the case scenario, discuss what primary and secondary medical diagnoses should be considered for Mr. M. Explain why these should be considered and what data is provided for support. 3)When performing your nursing assessment, discuss what abnormalities would you expect to find and why. 4)Describe the physical, psychological, and emotional effects Mr. M.’s current health status may have on him. Discuss the impact it can have on his family. 5)Discuss what interventions can be put into place to support Mr. M. and his family. 6)Given Mr. M.’s current condition, discuss at least four actual or potential problems he faces. Provide rationale for each. You are required to cite to a minimum of two sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and relevant to nursing practice. Referance https://lc.gcumedia.com/nrs410v/pathophysiology-clinical-applications-for-client-health/v1.1/#/chapter/2
Nursing essays den helps students cope with college assignments and write papers on a wide range of topics. We deal with academic writing, creative writing, and non-word assignments.
E MAIL:
Support@nursingessaysden.com
PHONE:
+1 (518) 460 – 4461
Online Chat 24/7