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P53 and cancer treatments

Please edit my paper as following use simple language so my teacher and the students could understand it, add a good statistic in the introduction about the cancer and use a clear thesis. Research Writing 28 October 2019 P53 and future of cancer treatment The health impact of certain disorders alters the quality of life (QOL) of many individuals. Especially, cancer is a special kind of disorder that has a severe life-threatening impact on life. Cancer affects many body systems, organs, and tissues. Cancer starts in cells that serve as the body’s building blocks. In general, a body synthesizes novel cells based on the needs then substitutes old cells that later encounter death. When this natural process undergoes aberration, novel cell continues to grow regardless of any need and old cells fail to die or go off. The additional cells later turn into a tumor mass (Cancer). A tumor may be of benign otherwise malignant types. Benign tumors do not lead to cancer whereas malignant ones lead to cancer. Malignant tumor based cells can affect the tissues in the nearby region. Very often, these abnormal cells can also undergo breakage and spread to different body parts. Research initiatives have been instrumental in discovering a gene, P53 (Cancer). Briefly, the p53 gene is commonly termed as the tumor suppressor gene. The activity of this p53 gene ceases the tumor formation. If a person inherits only one functional copy of the p53 gene from their parents, they are predisposed to cancer and usually develop several independent tumors in a variety of tissues in early adulthood. This condition is rare and is known as Li-Fraumeni syndrome. However, mutations in p53 are found in most tumor types, and so contribute to the complex network of molecular events leading to tumor formation. Researchers mapped p53 gene to chromosome 17. In a given cell, protein p53 forms binding with DNA. This again activates a different gene to give rise to a p21protein that in turn forms a link with a cdk2 (cell division-stimulating protein). Whenever p21 forms a tight linkage with cdk2 and this restricts the cell passage to the subsequent cell division stage. A mutant form of p53 could not form any bondage with DNA in a reliable manner, and thus a p21 protein cannot be fully ready to function as the cell division. Thus cells undergo division in an uncontrolled manner and form tumors (Genes and Disease, 1998). Importance of p53 gene:

Topic Public policies that affects nurse practitioners

Please provide at least 250 words on each questions. Thank you. 1. Consider a few public health policies that affect nurse practitioners. Select one piece of federal legislation and one piece of state legislation that impacts the nurse practitioner practice. Describe the considerations to keep in mind on the job, ramifications for violating the law, and any other important aspects. 2. In the current environment of health care reform, describe the role nurse practitioners have in shaping legislation. If you wrote a letter to your state representative, who would you be writing to and what points would you state to create a positive impression on the issues addressed? references: https://www.aanp.org/ https://www.aacn.org/ https://www.ncsbn.org/federal.htm https://www.govtrack.us/congress/members/AZ#representatives

The literature review will be double-spaced, and use Times New Roman font size 12, with one inch margins on each side of the page. No exceptions. The total length of the literature review will be no less than seven (7) pages and no more than twelve (12) pages (NOT including the cover or reference pages). APA style is required.You are required to use a minimum of ten (10) references of which at least seven (7) must be from peer-reviewed sources. Please read the movement project guidelines on files, for this project I picked training people living with Osteoarthritis since I want to become a physical therapist that’s a growing population.

Design nursing care strategies which incorporate genetic and genomic risk factors. You are feeling passionate about developing information to share with your clients and families that have positive genetic testing results.

Design nursing care strategies which incorporate genetic and genomic risk factors

Scenario
You are feeling passionate about developing information to share with your clients and families that have positive genetic testing results. A young couple approaches you concerned that they may have a child with Down syndrome as both the male and female in the relationship have siblings with Down syndrome. You decide to create an educational document that supports the family in their search for more information.

Instructions
Describe educational information that a couple may need to know before the birth of their baby. What testing can be recommended? How is this testing done and when in the gestation?
Additionally, After birth, what resources can be offered to this couple to care for their newborn with Down syndrome?
Finally, List and describe resources this family may access now and into the future to support care for their child with Down Syndrome into adulthood.

More details;